Kaposi’s sarcoma is malignant tumour of connective tissue..Kaposi’s sarcoma is an unusual and uncommon disease of blood vessels which occasionally manifests in the oral cavity.Kaposi’s sarcoma is an infectious granuloma or a retituloendothelial hyperplasia.
Clinical features:
Kaposi’s sarcoma may occur at any age but it is common in the fifth,sixth and seventh decades.The multiple skin lesions originate on the extremities but also involve the face and oral cavity and many visceral organs and lymphnodes.They may appear reddish or brownish-red nodules which may vary in size from a few millimeters to a centimeter or more in diameter and are less painful and tender.The lesions of the mucosa are identical in appearance with the cutaneous nodules.Cervical lymphnodes and salivary gland involvement is also seen..
Histologic features:
The lesion may consist of numerous small capillary type blood vessels which may or may not be blood containing.The lesions are extremely cellular consisting of proliferating masses of embryonic appearing spindle cells of varying size,shape and appearance showing occasional mitoses with hyperemic vascular slits.Inflammatory cell infiltration is seen.The development of the disease takes place in three stages:inflammation,granuloma and neoplasia.
Treatment and Prognosis:
Surgical eradication of the disease is dffcult because of the multiplicity of the lesions.X-ray radiation has been used for treatment.Chemotherapeutic agents have also been used beneficiallySEARCH " OTHER ARTICLES " ....